BDBM517139 6-isopropyl-5-[(4- methoxyphenyl)methyl]-1- tetrahydropyran-4-yl-pyrazolo[3,4- d]pyrimidin-4-one::US11104680, Example 8

SMILES COc1ccc(Cn2c(nc3n(ncc3c2=O)C2CCOCC2)C(C)C)cc1

InChI Key InChIKey=IVICMAQJTMYPDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517139   

LigandPNGBDBM517139(US11104680, Example 8 | 6-isopropyl-5-[(4- methoxy...)
Affinity DataIC50: 211nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517139(US11104680, Example 8 | 6-isopropyl-5-[(4- methoxy...)
Affinity DataIC50: 751nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517139(US11104680, Example 8 | 6-isopropyl-5-[(4- methoxy...)
Affinity DataIC50: 1.32E+3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent