BDBM517147 6-methyl-5-(p-tolylmethyl)-1- tetrahydropyran-4-yl-pyrazolo[4,3- c]pyridin-4-one::US11104680, Example 16

SMILES Cc1ccc(Cn2c(C)cc3n(ncc3c2=O)C2CCOCC2)cc1

InChI Key InChIKey=CXGGCYJPLGSTBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517147   

LigandPNGBDBM517147(US11104680, Example 16 | 6-methyl-5-(p-tolylmethyl...)
Affinity DataIC50: 71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517147(US11104680, Example 16 | 6-methyl-5-(p-tolylmethyl...)
Affinity DataIC50: 400nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517147(US11104680, Example 16 | 6-methyl-5-(p-tolylmethyl...)
Affinity DataIC50: 496nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent