BDBM518001 (2R)-8-(1-acetylazetidin-3-yl)oxy-4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy propyl]-2-methyl-2,3-dihydro-1,4-benzoxazepin-5-one::US11111237, Example 142::US11725001, Example 142

SMILES C[C@@H]1CN(C[C@H](O)CN2CCc3ccccc3C2)C(=O)c2ccc(OC3CN(C3)C(C)=O)cc2O1

InChI Key InChIKey=LXCVPOMMROXYLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518001   

TargetProtein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518001(US11111237, Example 142 | (2R)-8-(1-acetylazetidin...)
Affinity DataIC50: 50nMAssay Description:Experimental procedure: The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM518001(US11111237, Example 142 | (2R)-8-(1-acetylazetidin...)
Affinity DataIC50: 50nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent