BDBM520047 (4R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((8aS)-2-(2-(1-methylpyrrolidin-2-yl)-1H-benzo[d]imidazol-5-yl)-3-oxohexahydroimidazo[1,5-a]pyrazin-7(1H)-yl)methyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate::US11142527, Example 108

SMILES COC(=O)C1=C(CN2CCN3C(=O)N(c4ccc5[nH]c(C6CCCN6C)nc5c4)C[C@@H]3C2)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl

InChI Key InChIKey=BOMBWIMOEBFWET-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520047   

TargetLarge envelope protein(HBV-D)
Sunshine Lake Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 520047BDBM520047((4R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((8aS)-...)
Affinity DataEC50:  6.80nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent