BDBM520651 US11147816, PD318088::US11701360, PD318088

SMILES OCC(O)CONC(=O)c1cc(Br)c(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=XXSSGBYXSKOLAM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520651   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
Genuv

US Patent

LigandBDBM520651(US11147816, PD318088 | US11701360, PD318088)Copy SMILESCopy InChI

Affinity DataIC50:  1.40nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails US Patent
PDB3D Structure (crystal)
Copy BDB DOI
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Genuv

US Patent

LigandBDBM520651(US11147816, PD318088 | US11701360, PD318088)Copy SMILESCopy InChI

Affinity DataIC50:  1.40nMAssay Description:The IC50 for MEK1 and 2 can be measured by methods in references such as [Yamaguchi et al. (2011) International Journal of Oncology 39:23-31].More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails US Patent
PDB3D Structure (crystal)
Copy BDB DOI
Copy reaction URL