BDBM521662 US11149054, Compound 4A77

SMILES CC[C@]1(O)CC[C@H]2[C@@H](CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CC[C@H](O)C(C)C)[C@@]4(C)CC[C@H]23)C1

InChI Key InChIKey=BDESKOKFNAGOOM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521662   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Sage Therapeutics

US Patent
LigandPNGBDBM521662(US11149054, Compound 4A77)
Affinity DataEC50:  285nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Sage Therapeutics

US Patent
LigandPNGBDBM521662(US11149054, Compound 4A77)
Affinity DataEC50:  427nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent