BDBM522063 N-[3-[6-(difluoromethoxy)- 1,2-benzothiazol-5-yl]-1H- pyrazol-4-yl]pyrazolo[1,5- a]pyrimidine-3- carboxamide; formic acid::US11155557, Example 153

SMILES FC(F)Oc1cc2sncc2cc1-c1n[nH]cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=QRORYECTXLINFG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522063   

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandPNGBDBM522063(N-[3-[6-(difluoromethoxy)- 1,2-benzothiazol-5-yl]-...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandPNGBDBM522063(N-[3-[6-(difluoromethoxy)- 1,2-benzothiazol-5-yl]-...)
Affinity DataKi:  0.150nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent