BDBM522138 US11160797, Example 46

SMILES CC(C)n1cc(ccc1=O)-c1cncc(n1)-c1ccc2N(C)C(=O)Cc2c1

InChI Key InChIKey=MPUAEAFJNJDWLV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 522138   

TargetActivin receptor type-1 [172-499](Human)
Novartis

US Patent
LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  150nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  930nMAssay Description:Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1 [172-499](Human)
Novartis

US Patent
LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  120nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  2.50E+3nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  620nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1 [162-503](Human)
Novartis

US Patent
LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  5.00E+3nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1 [172-499,R206H](Human)
Novartis

US Patent
LigandPNGBDBM522138(US11160797, Example 46)
Affinity DataIC50:  110nMAssay Description:Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent