BDBM522236 US11161839, Example 1u

SMILES CNC(=O)c1cc(Nc2ccc3n(C)c(=O)cc(NC(C)(C)c4ncccn4)c3c2)c(C#N)c(Cl)n1

InChI Key InChIKey=JXBIQVFMBICIEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522236   

TargetB-cell lymphoma 6 protein [5-129](Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522236(US11161839, Example 1u)
Affinity DataIC50:  30.9nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetB-cell lymphoma 6 protein [5-129](Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522236(US11161839, Example 1u)
Affinity DataIC50:  36.3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent