BDBM522255 US11161839, Example 7d

SMILES CNC(=O)c1cc(Nc2ccc3n(C)c(=O)cc(NC(C)(C)COC)c3c2)c(C#N)c(Cl)n1

InChI Key InChIKey=FRXXZQQMRPDCOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522255   

TargetB-cell lymphoma 6 protein [5-129](Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522255(US11161839, Example 7d)
Affinity DataIC50:  141nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent