BDBM522284 US11161839, Example 10e
SMILES CC(Nc1cc(=O)n(C)c2ccc(Nc3ccnc(Cl)c3C#N)cc12)c1ncc(cn1)C1CC1
InChI Key InChIKey=FHLDBZWADXDVDT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 522284
TargetB-cell lymphoma 6 protein [5-129](Homo sapiens (Human))
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
Affinity DataIC50: 53.7nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human nanoLuc-tagged BCL6 expressed in HEK293T cells coexpressing HaloTag-SMRT using NanoBRET furimazine substrate incubated for 6 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human BCL6 (5 to 129 residues) expressed in Escherichia coli BL21-AI using BCOR-AF633 peptide as substrate measured after 2 hrs by TR-F...More data for this Ligand-Target Pair