BDBM522406 2-(cis-3-fluoro-3-methylcyclobutyl)-1-[(3R)-1-methylpyrrolidin-3-yl]-1H-imidazo[-c]quinoline-8-carbonitrile::US11161844, Example 22

SMILES CN1CCC(C1)n1c(nc2cnc3ccc(cc3c12)C#N)C1C[C@@](C)(F)C1

InChI Key InChIKey=KSSKOZWKIFLBTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522406   

LigandPNGBDBM522406(US11161844, Example 22 | 2-(cis-3-fluoro-3-methylc...)
Affinity DataIC50: 14.2nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

LigandPNGBDBM522406(US11161844, Example 22 | 2-(cis-3-fluoro-3-methylc...)
Affinity DataIC50: 36.5nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent