BDBM523216 US11161855, Example 72 (second peak)

SMILES N#CC[C@H]1CC[C@](CO)(n2cnc3cnc4ccsc4c32)CC1

InChI Key InChIKey=LQARLKXPHUKEDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523216   

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 523216BDBM523216(US11161855, Example 72 (second peak))
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 523216BDBM523216(US11161855, Example 72 (second peak))
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
US Patent