BDBM523532 US11136311, Compound 21

SMILES CC1(CO)CNc2c(C#N)cc(-c3ccnc(Nc4cc[nH]n4)n3)cc21

InChI Key InChIKey=VNTFENAYYDTJAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523532   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 523532BDBM523532(US11136311, Compound 21)
Affinity DataIC50: 2.90nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent