BDBM524380 4-(1-((1-(2-hydroxyethyl)piperidin-4- yl)methyl)-5-(1-methyl-1H-indazol-5-yl)- 1H-pyrrolo[2,3-c]pyridin-4-yl)benzonitrile::US11168082, Cpd. No. 78

SMILES Cn1ncc2cc(ccc12)-c1ncc2n(CC3CCN(CCO)CC3)ccc2c1-c1ccc(cc1)C#N

InChI Key InChIKey=UIVYTWHBPGEYLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524380   

TargetLysine-specific histone demethylase 1A(Human)
University of Michigan

US Patent
LigandPNGBDBM524380(US11168082, Cpd. No. 78 | 4-(1-((1-(2-hydroxyethyl...)
Affinity DataIC50: 14.3nMAssay Description:Human recombinant LSD1 protein expressed in E. coli cells was purchased from Active Motif (Carlsbad, Calif.). Biotin-labeled Histone H3K4Me peptide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent