BDBM524446 2-((2S,4R)-4-amino-1-(5- chlorobenzo[d]thiazole-2- carbonyl)pyrrolidin-2-yl)-N-((S)-6- guanidino-1-(methylamino)-1- oxohexan-2-yl)thiazole-4-carboxamide::US11168083, Example 45

SMILES CNC(=O)[C@H](CCCCNC(=N)N)NC(=O)c1csc([C@@H]2C[C@@H](N)CN2C(=O)C2=NC3C=C(Cl)C=CC3S2)n1

InChI Key InChIKey=GJGFBTQCJROWAU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 524446   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 524446BDBM524446(2-((2S,4R)-4-amino-1-(5- chlorobenzo[d]thiazole-2-...)
Affinity DataEC50: <100nMAssay Description:Plasma Kallikrein: The example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent