BDBM526504 US11186566, Compound 43
SMILES C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2ccccc2Cl)-n2ccc(OCCC3(CC3)C(F)(F)F)n2)C(C)(C)C1
InChI Key InChIKey=HWRRKFSXPSUGLD-SFHVURJKSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 526504
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 50nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: <100nMAssay Description:The assay utilizes fluorescent voltage sensing dyes to measure changes in membrane potential using a fluorescent plate reader (e.g., FLIPR III, Molec...More data for this Ligand-Target Pair