BDBM527547 US11186587, Example 30

SMILES COc1ccccc1C(Cn1c(=O)n(-c2cc(C(=O)O)ccc2F)c(=O)c2c(C)c(-c3ncco3)sc21)OC1CCOCC1

InChI Key InChIKey=ZSCVUPOHGVWVCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 527547   

TargetAcetyl-CoA carboxylase 1(Human)
Nanjing Sanhome Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 527547BDBM527547(US11186587, Example 30)
Affinity DataIC50: 7.97nMAssay Description:4.5 μL of 2.2×ACC1 enzyme (2 nM) working solution was added to a 384-well plate; and then 0.5 μL of different concentrations of compound we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent