BDBM5280 5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine::N-(1,3-Thiazol-2-yl)pyridin-2-amine 1::aminothiazole 3

SMILES N(c1ncc(s1)-c1ccccc1)c1ccccn1

InChI Key InChIKey=YBTSWXCHAPCPGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5280   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5280(5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine | N-...)
Affinity DataIC50:  7nMpH: 7.4 T: 22°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM5280(5-phenyl-N-(pyridin-2-yl)-1,3-thiazol-2-amine | N-...)
Affinity DataIC50:  7nMpH: 7.4 T: 22°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed