BDBM528220 US11180494, Example 108::US11180494, Example 93

SMILES CC(C)(CC#N)C(=O)NC(CCO[C@H]1C[C@H](CCc2ccc3CCCNc3n2)C1)C(O)=O

InChI Key InChIKey=RFJUXLOWQQTBRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 528220   

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM528220(US11180494, Example 93 | US11180494, Example 108)
Affinity DataIC50: 50nMAssay Description:The biochemical potency of compounds was determined using a proximity-based assay (ALPHASCREEN , Perkin Elmer, Waltham, Mass.) as described previousl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM528220(US11180494, Example 93 | US11180494, Example 108)
Affinity DataIC50: 150nMAssay Description:The biochemical potency of compounds was determined using a proximity-based assay (ALPHASCREEN , Perkin Elmer, Waltham, Mass.) as described previousl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent