BDBM528477 5-(Benzo[d][1,3]dioxol-5-yl)-2-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one::US11191765, Example 15

SMILES O=c1cc(-c2ccc3c(c2)OCO3)[nH]c2nc(-c3ccc(Cl)cc3)nn12

InChI Key InChIKey=RAOAMFJWZVSJEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 528477   

LigandChemical structure of BindingDB Monomer ID 528477BDBM528477(US11191765, Example 15 | 5-(Benzo[d][1,3]dioxol-5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 528477BDBM528477(US11191765, Example 15 | 5-(Benzo[d][1,3]dioxol-5-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent