BDBM528750 US11198681, Compound I-74

SMILES COc1cc(cc2nc(-c3ccc(C#N)n3Cc3ccccc3)n(C)c12)C(=O)N1C[C@H]2CC[C@@H]1[C@@H]2N

InChI Key InChIKey=GLXZWUNVEKFCAF-YBGOQADZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 528750   

TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528750(US11198681, Compound I-74)
Affinity DataIC50:  3.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Mus musculus)
Padlock Therapeutics

US Patent
LigandPNGBDBM528750(US11198681, Compound I-74)
Affinity DataIC50:  7.50E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Padlock Therapeutics

US Patent
LigandPNGBDBM528750(US11198681, Compound I-74)
Affinity DataIC50:  3.00E+3nMAssay Description:Compounds were solubilised in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent