BDBM531987 US11208403, Example 64

SMILES COc1cc(ccc1OC[C@H]1COCCO1)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(C)cn3)c2=O)cc1F

InChI Key InChIKey=ZOEILZXFYPPMTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 531987   

TargetTyrosine-protein kinase receptor UFO(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM531987(US11208403, Example 64)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of AXL (unknown origin) preincubated with compound for 20 mins followed by ATP addition and measured after 45 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM531987(US11208403, Example 64)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of AXL (unknown origin) by kinase profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM531987(US11208403, Example 64)
Affinity DataIC50: 4.80nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM531987(US11208403, Example 64)
Affinity DataIC50: 216nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent