BDBM532367 US11214540, Example 25

SMILES CC(CC(C)(C)c1ccc(F)cc1)N1CCC(O)CC1

InChI Key InChIKey=XBSVHXNOQTWHKM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 532367   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Cognition Therapeutics

US Patent
LigandPNGBDBM532367(US11214540, Example 25)
Affinity DataKi:  2.30nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM532367(US11214540, Example 25)
Affinity DataKi:  10nMAssay Description:The affinity of test compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled sigma-2 or sigma-1 lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
US Patent