BDBM533760 Preparation of 6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)nicotinamide ::US11225492, Compound 18
SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)C(=O)NCCCCCCC(=O)NO)nc2n(C2CCCC2)c1=O
InChI Key InChIKey=LZBBJSVJRPQJKQ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 533760
Affinity DataIC50: <50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair