BDBM53434 4-(1-piperidinyl)-1,2-naphthalenedione::4-(1-piperidinyl)naphthalene-1,2-dione::4-piperidin-1-ylnaphthalene-1,2-dione::4-piperidino-1,2-naphthoquinone::MLS001179188::Nonacylated oxime, 23::SMR000476613::cid_3393623

SMILES O=C1C=C(N2CCCCC2)c2ccccc2C1=O

InChI Key InChIKey=CJXORYYEEAJZSR-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 53434   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mouse)
Brigham and Women'S Hospital

LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  7.80E+4nMpH: 7.6 T: 25°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataEC50:  1.78E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  1.34E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosyl-DNA phosphodiesterase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  5.32E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCaspase-9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  1.46E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  2.12E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53434(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Affinity DataIC50:  2.39E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay