BDBM534923 Preparation of (2S,4R)-4-fluoro-N-((5′-fluoro-6-(trifluoromethyl)-3,4′-bipyridin-2′-yl)methyl)-1-(4-fluorophenylsulfonyl)pyrrolidine-2-carboxamide::US11236046, Example 140::US11236046, Example 9

SMILES F[C@@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(c(F)cn1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=ZXWITAARDYYKLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534923   

LigandPNGBDBM534923(Preparation of (2S,4R)-4-fluoro-N-((5′-fluor...)
Affinity DataIC50: 20nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

LigandPNGBDBM534923(Preparation of (2S,4R)-4-fluoro-N-((5′-fluor...)
Affinity DataIC50: 20nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent