BDBM534924 Preparation of (2S,4R)-4-fluoro-N-((5-fluoro-6′-(trifluoromethyl)-2,3′-bipyridin-4-yl)methyl)-1-(4-fluorophenylsulfonyl)pyrrolidine-2-carboxamide::US11236046, Example 141::US11236046, Example 8

SMILES F[C@@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(ncc1F)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=XSCCGKSIBNQWIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534924   

LigandPNGBDBM534924(Preparation of (2S,4R)-4-fluoro-N-((5-fluoro-6R...)
Affinity DataIC50: 17nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

LigandPNGBDBM534924(Preparation of (2S,4R)-4-fluoro-N-((5-fluoro-6R...)
Affinity DataIC50: 68nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent