BDBM534954 Preparation of (2R,3S) N-([2-cyano-5-[2-(trifluoromethyl)pyrimidin-5-yl]phenyl]methyl)-3-fluoro-1-[(4-fluorobenzene)sulfonyl]pyrrolidine-2-carboxamide::US11236046, Example 38

SMILES F[C@H]1CCN([C@@H]1C(=O)NCc1cc(ccc1C#N)-c1cnc(nc1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=ZKTUMHFHLXSNAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534954   

LigandPNGBDBM534954(Preparation of (2R,3S) N-([2-cyano-5-[2-(trifluoro...)
Affinity DataIC50: 14nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent