BDBM534966 Preparation of (2S,4R)-4-fluoro-N-(3-fluoro-5-(5-(trifluoromethyl)pyrazin-2-yl)benzyl)-1-((4-fluorophenyl)sulfonyl)-4-methylpyrrolidine-2-carboxamide::US11236046, Example 47

SMILES C[C@@]1(F)C[C@H](N(C1)S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(F)cc(c1)-c1cnc(cn1)C(F)(F)F

InChI Key InChIKey=QLZXIMYXMVOVAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534966   

LigandPNGBDBM534966(Preparation of (2S,4R)-4-fluoro-N-(3-fluoro-5-(5-(...)
Affinity DataIC50: 11nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent