BDBM534977 (2S,4R)-4-fluoro-1-(4- fluorophenyl)sulfonyl-N-[[2-[2- hydroxy-4- (trifluoromethyl)phenyl]-4- pyridyl]methyl]pyrrolidine-2- carboxamide::US11236046, Example 57

SMILES Oc1cc(ccc1-c1cc(CNC(=O)[C@@H]2C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)ccn1)C(F)(F)F

InChI Key InChIKey=SUOFUNIWBNOTLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534977   

LigandPNGBDBM534977((2S,4R)-4-fluoro-1-(4- fluorophenyl)sulfonyl-N-[[2...)
Affinity DataIC50: 5nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent