BDBM534989 Preparation of (2S,4R) N-[[4-(2,2-difluoro-6-azaspiro[2.5]octan-6-yl)-5-fluoro-2-pyridyl]methyl]-4-fluoro-1-(4-fluorophenyl)sulfonyl-pyrrolidine-2-carboxamide::US11236046, Example 69

SMILES F[C@@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(N2CCC3(CC3(F)F)CC2)c(F)cn1

InChI Key InChIKey=GVDCWIWNLLLASC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534989   

LigandPNGBDBM534989(Preparation of (2S,4R) N-[[4-(2,2-difluoro-6-azasp...)
Affinity DataIC50: 14nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent