BDBM534992 Preparation of (2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonyl-N-[[4-[5-(trifluoromethyl)-2-pyridyl]-2-pyridyl]methyl]pyrrolidine-2-carboxamide::US11236046, Example 72

SMILES F[C@H]1CCN([C@@H]1C(=O)NCc1cc(ccn1)-c1ccc(cn1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=ZPXMWXHOFAMXMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534992   

LigandPNGBDBM534992(Preparation of (2R,3S)-3-fluoro-1-(4-fluorophenyl)...)
Affinity DataIC50: 7nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent