BDBM535031 Preparation of (2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonyl-N-[[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]methyl]pyrrolidine-2-carboxamide::US11236046, Example 111

SMILES F[C@H]1CCN([C@@H]1C(=O)NCc1cc(ncn1)-c1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=GMVVWDBILLJHLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535031   

LigandPNGBDBM535031(Preparation of (2R,3S)-3-fluoro-1-(4-fluorophenyl)...)
Affinity DataIC50: 7nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent