BDBM535045 Preparation of (2S,4R)-4-fluoro-1-[(4-fluorobenzene)sulfonyl]-N-([3-methoxy-1-[6-(trifluoromethyl)pyridin-3-yl]-1H-pyrazol-4-yl]methyl)-2-methylpyrrolidine-2-carboxamide::US11236046, Example 125

SMILES COc1nn(cc1CNC(=O)[C@]1(C)C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=DCVSFXIYOAFCQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535045   

LigandPNGBDBM535045(Preparation of (2S,4R)-4-fluoro-1-[(4-fluorobenzen...)
Affinity DataIC50: 9nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent