BDBM535102 Preparation of (1R,5S)-4-(4-fluorophenyl)sulfonyl-N-[[3-fluoro-5-[2-(trifluoromethyl)pyrimidin-5-yl]phenyl]methyl]-4-azabicyclo[3.1.0]hexane-5-carboxamide::US11236046, Example 181

SMILES Fc1ccc(cc1)S(=O)(=O)N1CC[C@@H]2C[C@]12C(=O)NCc1cc(F)cc(c1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=PRCKQIDYJROCLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535102   

LigandPNGBDBM535102(Preparation of (1R,5S)-4-(4-fluorophenyl)sulfonyl-...)
Affinity DataIC50: 10nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent