BDBM535104 Preparation of (1S,2S,5R) N-(2-fluoro-5-(2-(trifluoromethyl)pyrimidin-5-yl)benzyl)-3-((4-fluorophenyl)sulfonyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide::US11236046, Example 183

SMILES Fc1ccc(cc1)S(=O)(=O)N1C[C@@H]2C[C@@H]2[C@H]1C(=O)NCc1cc(ccc1F)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=PXSQFGAZGBJIGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535104   

LigandPNGBDBM535104(Preparation of (1S,2S,5R) N-(2-fluoro-5-(2-(triflu...)
Affinity DataIC50: 3nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent