BDBM535107 Preparation of (2S,5S)-1-(4-fluorophenylsulfonyl)-5-methyl-N-((2-(2-(trifluoromethyl)pyrimidin-5-yl)pyridin-4-yl)methyl)pyrrolidine-2-carboxamide::US11236046, Example 186

SMILES C[C@H]1CC[C@H](N1S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1ccnc(c1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=GFSKJMFCKOFCET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535107   

LigandPNGBDBM535107(Preparation of (2S,5S)-1-(4-fluorophenylsulfonyl)-...)
Affinity DataIC50: 4nMAssay Description:IC50s (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing...More data for this Ligand-Target Pair
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Date in BDB:
6/6/2022
Entry Details
US Patent