BDBM535324 WO2022021841, 43

SMILES CC1(C)[C@H]2CN(C([C@@H]12)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O)C(=O)COc1ccc(Cl)cc1

InChI Key InChIKey=UJTKRTAWEQKHLE-VVWDEGDPSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 535324   

TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

WIPO
LigandPNGBDBM535324(WO2022021841, 43)
Affinity DataKi:  9nMAssay Description:SARS-CoV-2 Mpro (final concentration 750 nM) plus every compound in 25 uL of buffer (20 mM Tris-HCl, pH 7.5, 150mM NaCl，1mM EDTA，2mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022021841


TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

WIPO
LigandPNGBDBM535324(WO2022021841, 43)
Affinity DataEC50:  530nMAssay Description:Vero E6 cells were plated at 20,000 cells/well in a 96-well plate. 24hr later, medium containing a dose response of NHC was added concurrent with SAR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails WIPO WO2022021841