BDBM535758 US11236096, Example 34

SMILES CC(C)n1nc(C(=O)Nc2cc(C)n[nH]2)c2c(N)ncnc12

InChI Key InChIKey=BZUNLTWIUMVYTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 535758   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM535758(US11236096, Example 34)
Affinity DataIC50:  0.290nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against RET kinase activity, the website of AnaSpec states that...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM535758(US11236096, Example 34)
Affinity DataIC50:  1.25E+3nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against LCK kinase activity, the website of AnaSpec states that...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM535758(US11236096, Example 34)
Affinity DataIC50:  9.90nMAssay Description:Regarding the conditions for measurement of in vitro inhibitory activity of compounds against SRC kinase activity, the price list of LabChip-series c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent