BDBM535908 3-(5-((4-([2,2'-bithiophen]-5- ylmethyl)piperazin-1-yl)methyl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-05624

SMILES O=C1CCC(N2Cc3cc(CN4CCN(Cc5ccc(-c6cccs6)s5)CC4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=RHMXUDVZPAPABP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535908   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 535908BDBM535908(3-(5-((4-([2,2'-bithiophen]-5- ylmethyl)piperazin-...)
Affinity DataIC50: 470nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent