BDBM536226 US11242344, Example 108.2

SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C1=NC(=O)[C@](C)(N1)c1ccc(cc1)-c1cccc(=O)n1C)c1cc(C)no1

InChI Key InChIKey=NVXRTBAQPIGSRM-FNPDAKPFSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536226   

LigandPNGBDBM536226(US11242344, Example 108.2)
Affinity DataKd:  3.95E+3nMAssay Description:Using a Biacore T200, Avidin tagged VHL co-expressed with Elongins B and C were immobilized to a Biacore SA chip in running buffer without DMSO. Comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536226(US11242344, Example 108.2)
Affinity DataIC50:  1.10E+4nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent