BDBM536297 US11242344, Example 1004.4
SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@H](C(C)C)C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C
InChI Key InChIKey=GDUPOTCODJXPBK-JTZWRRJCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 536297
Affinity DataIC50: 1.00E+5nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
TargetElongin-B/Elongin-C [17-112]/von Hippel-Lindau disease tumor suppressor [55-213](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 6.25E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair