BDBM536297 US11242344, Example 1004.4

SMILES COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOCC#CC#CCOc1cc(on1)[C@H](C(C)C)C(=O)N1C[C@H](O)C[C@@H]1C1=NC(=O)[C@@](C)(N1)c1ccc(cc1)-c1scnc1C

InChI Key InChIKey=GDUPOTCODJXPBK-JTZWRRJCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536297   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM536297(US11242344, Example 1004.4)
Affinity DataIC50:  1.00E+5nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM536297(US11242344, Example 1004.4)
Affinity DataIC50:  6.25E+3nMAssay Description:The binding of test compounds to the VHL Elongin B/C complex was measured using a fluorescence polarization tracer competition assay. The VHL/Elongin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent