BDBM536303 (E)-5-methyl-2-(5-((4-methylpiperazin-1-yl)sulfonyl)-2-propoxyphenyl)-4-oxo-7-propyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carbaldehyde O-methyl oxime::US11242347, Compound 1o::US11897890, Compound lo

SMILES CCCOc1ccc(cc1-c1nn2c(CCC)c(\C=N\OC)c(C)c2c(=O)[nH]1)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=JASADCYXJIVUCI-WPWMEQJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536303   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536303((E)-5-methyl-2-(5-((4-methylpiperazin-1-yl)sulfony...)
Affinity DataIC50:  5.30nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandPNGBDBM536303((E)-5-methyl-2-(5-((4-methylpiperazin-1-yl)sulfony...)
Affinity DataIC50:  0.530nMAssay Description:Experimental protocol: The test compound, i.e the compound of the present invention, reference compound or water (control) are added to a buffer cont...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent