BDBM536304 (E)-2-(5-((4-(2-hydroxyethyl)piperidin-1-yl)sulfonyl)-2-propoxyphenyl)-5-methyl-4-oxo-7-propyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carbaldehyde oxime::US11242347, Compound 1r

SMILES CCCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1-c1nn2c(CCC)c(/C=N/O)c(C)c2c(=O)[nH]1

InChI Key InChIKey=PNBAERNLEZJKFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536304   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Topadur Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 536304BDBM536304((E)-2-(5-((4-(2-hydroxyethyl)piperidin-1-yl)sulfon...)
Affinity DataIC50: 1.60nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent