BDBM536328 Step 1: Preparation of 3-[[(6-chloro-5-nitro-2-propylsulfanyl-pyrimidin-4-yl)amino]methyl]benzonitrile::US11242345, Example 18

SMILES CCCSc1nc(Cl)c(c(NCc2cccc(c2)C#N)n1)[N+]([O-])=O

InChI Key InChIKey=HBVIITUOCCASKD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536328   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM536328(Step 1: Preparation of 3-[[(6-chloro-5-nitro-2-pro...)
Affinity DataEC50:  47nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
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Date in BDB:
6/10/2022
Entry Details
US Patent