BDBM536343 4-[[6-Amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin-9-yl]methyl]benzonitrile (compound 32) and 4-[[6-amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin-9-yl]methyl]benzamide (compound 33)::US11242345, Example 32

SMILES CCCS(=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(cc3)C#N)c2n1

InChI Key InChIKey=OOTVBBLVGZVFGS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536343   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM536343(4-[[6-Amino-8-oxo-2-(propylsulfonimidoyl)-7H-purin...)
Affinity DataEC50:  54nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
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Date in BDB:
6/10/2022
Entry Details
US Patent