BDBM536357 US11242345, Example 70-A

SMILES CC[S@](=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(Cl)cc3)c2n1

InChI Key InChIKey=UTHROXJUYVNHHL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 536357   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM536357(US11242345, Example 70-A)
Affinity DataEC50:  54nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM536357(US11242345, Example 70-A)
Affinity DataEC50: >1.00E+6nMAssay Description:A stable HEK-Blue-hTLR8 cell line was purchased from InvivoGen (Cat. #: HEK-Blue-htlr8, San Diego, Calif., USA). These cells were designed for studyi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2022
Entry Details
US Patent