BDBM537042 (E)-3-(5-((4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-4-((1-ethyl-1H-imidazol-5-yl)methyl)-4H-1,2,4-triazol-3-yl)acrylic acid ::US11897851, Compound 142

SMILES CCn1cncc1Cn1c(CN2CCC(CC2)c2cccc3OC(C)(Oc23)c2ccc(Cl)cc2F)nnc1\C=C\C(O)=O

InChI Key InChIKey=JCUHAGOTXPTEHB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537042   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM537042((E)-3-(5-((4-(2-(4-chloro-2-fluorophenyl)-2-methyl...)
Affinity DataEC50:  0.0120nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent