BDBM537095 (E)-3-(2-((4-((S)-2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-((S)-2-methoxypropyl)-1H-imidazol-5-yl)acrylic acid (Compound 172a) and (E)-3-(2-((4-((S)-2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-((R)-2-methoxypropyl)-1H-imidazol-5-yl)acrylic acid ::US11897851, Compound 172b

SMILES CO[C@H](C)Cn1c(CN2CCC(CC2)c2cccc3O[C@@](C)(Oc23)c2ccc(Cl)cc2F)ncc1\C=C\C(O)=O

InChI Key InChIKey=RGHWMAYLWXPKQF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537095   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM537095((E)-3-(2-((4-((S)-2-(4-chloro-2-fluorophenyl)-2-me...)
Affinity DataEC50:  0.0210nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent